Supercoil-It™
A Breakthrough in Plasmid Purification
Description:
The Supercoil-It plasmid purification system produces virtually
100% supercoiled plasmid from any plasmid preparation, regardless
of the initial percentage of open circular plasmid, plasmid
size, plasmid sequence, and plasmid source. This is accomplished
by enzymatically converting virtually all open circular
plasmid to supercoiled plasmid. Because this technology
is based on enzymatic conversion, and not separation of
open circular plasmid from supercoiled plasmid, there is
no loss of plasmid in the Supercoil-It purification reaction.
Supercoil-It is NOT for use in purifying plasmid for human
therapeutic use.
Two Versions: Supercoil-It
is sold in two versions: HS and MS. Supercoil-It HS
does not contain topoisomerase I. Supercoil-It HS produces
highly supercoiled plasmid which is supercoiled by DNA
gyrase to its thermodynamic limit. Supercoil-It MS does
contain topoisomerase
I. Supercoil-It MS produces moderately supercoiled plasmid.
Supplied:Both
Supercoil-It HS and Supercoil-It MS are supplied with
sufficient 20X Supercoil-It Buffer. Instructions for
use are included.
Low Price: Purifies 150
mg of plasmid for only $200.
Patent Pending: Supercoil-It
is patent pending worldwide
